KADAR SERUM KREATININ DAN KALIUM PASIEN DENGAN DAN TANPA DIABETES JENIS (TIPE) II

Abstract

Hyperkalemia is a metabolic disorder caused by either renal insufficiency for potassium excretion (like in renal failure), the
dysmechanism of potassium transportation into the intracellular space (regards on the hyperglycemia status) or combinations of those
etiologies. In nephropathy diabetic patients, hyporeninemic hypoaldosteronism syndrome might also be the etiology resulting from the
high potassium level. The objective of the present study was to evaluate the correlation between the serum creatinine and potassium
level in patient with and without type II diabetes. The data of this study were drawn from patients admitted to the laboratory for the
measurement of serum creatinine and potassium with or without the measurement of blood glucose level at the Clinical Pathology
Laboratory of Moewardi Hospital in Surakarta. The subjects were then classified into two groups: A (non-diabetic patients) and B
(diabetic patients). The data were analyzed statistically with T-student test and Pearson Correlation test based on the total samples, per
each group (A and B groups) and the diabetic status (only B group) one. In this study so far it was found that the serum creatinine and
potassium level were significantly correlated in the total sample and group A analysis (p<0.05). Surprisingly, the correlation was not
found or very weak in group B (p>0.05). Furthermore, no correlation was found in the analysis based on the diabetic status among
the B group subjects (p>0.05). It can be suggested that other factors may play a significant influence on the correlation between the
hyperglycemia state, renal failure and serum potassium level in diabetic patients. Further detailed analysis should be warranted to
elucidate those factors.