NILAI DIAGNOSTIK MALARIA ANTIGEN CASSETTE PENYAKIT MALARIA

Abstract

Malaria is an endemic disease in many countries. In 103 endemic countries with around 2.5 billion population, 1−3 million death
cases were reported every year. Clinical criteria and blood smear established the diagnosis of malaria. ICT (imuno chromatography
test) is needed in peripheral areas where there are no experienced laboratory technicians. The procedure is simple, practical, easy, as
well as quicker than the conventional method, and no experienced technicians are needed this ICT advantages. The aim of this study is
to know the diagnostic value of Malaria Antigen Cassette with microscopic examination as the gold standard examination of malaria.
This research used observational cross-sectional method This study was done in Nusa Tenggara Barat during May−June 2008. Blood
samples were taken by finger prick in patients with Malaria symptoms: fever, chill and sweating, followed by examining the blood smear
by Malaria Antigen Cassette from Focus Diagnostic. The diagnostic value was then evaluated by calculating the sensitivity, specificity,
positive predictive value as well as the negative predictive value. The diagnostic value of Malaria Antigen Cassette in patients with
malaria falciparum was found as follows: sensitivity 95.2%, specificity 100%, positive predictive value 100%, and negative predictive
value 97.6%. The diagnostic value of Malaria Antigen Cassette in patients other types than malaria falciparum was as follows: sensitivity
94.8%, specificity 100%, positive predictive value 100%, and negative predictive value 95.3%. The diagnostic value of Malaria Antigen
Cassette was very high in diagnosing malaria falciparum compared to other types than malaria falciparum.