D-DIMER PENDERITA SINDROM KORONER AKUT DAN STENOSIS

Birhasani ., Lisyani B S, Ria T

Abstract


Acute coronary syndrome (ACS) is the multisystem of coronary artery disease. The clinical manifestation of ACS is acute myocardial
infarction (AMI). About 90% coronary attack is caused by thrombus occlusion in coronary artery. The suspect of thrombosis can be
diagnosed definitely by Angiography, but it is invasive. D-dimer used to measure thrombosis abnormality and fibrinolisys. The result of
their correlation between D-dimer with ACS is still controversived. The aim of this research is to analyse, the different between plasma
D-dimer level ACS with stenosis ≥ 50% and stenosis < 50%. This study used a cross sectional design. The study consist of seventeen
specimen ACS with stenosis ≥ 50% and 17 specimen with stenosis < 50%. Plasma D-dimer level was measured with quantitative
agglutination latex method. An independent t-test statistical analysis is used in this study. The average Plasma D-dimer of ACS with
stenosis ≥ 50% is 960.2 ± 404.99 µg/L thus ACS with stenosis < 50% is 300.3 ± 128.75 µg/L (p = 0.00). The plasma D-dimer level
of ACS with stenosis ≥ 50% is more significant than ACS with stenosis < 50%.


Keywords


Stenosis, D-dimer, acute coronary syndrome

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DOI: http://dx.doi.org/10.24293/ijcpml.v17i3.1092

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