ANALISIS KADAR OSTEOKALSIN SERUM OSTEOPENIA DAN OSTEOPOROSIS

Authors

  • N Sennang AN
  • Mutmainnah Mutmainnah
  • RDN Pakasi
  • Hardjoeno Hardjoeno

DOI:

https://doi.org/10.24293/ijcpml.v12i2.841

Keywords:

osteocalcin, osteopenia, osteoporosis

Abstract

Osteoporosis is a metabolic bone disease, characterized by decreased of bone mass density. Its incidence is higher in older population.
Serum osteocalcin level is related to the rate of bone turnover. To analyze serum osteocalcin level on osteopenic and osteoporosis subjects.
We examined 61 subjects for detecting osteopenia and osteoporosis by Sahara densitometer and measuring serum osteocalcin level by
Elecsys N-MID Osteocalsin Assay test. Of 21 men and 40 women, prevalence of osteopenia and osteoporosis were higher in women
(57.5% and 32.5%) than men (42.9% and 23.8%). Most of osteoporosis subjects were in ≥ 60 years group and osteopenic subjects were
in 50–59 years group (p<0.05). Mean of serum osteocalcin on osteoporosis subjects (26.70 ng/mL) was higher than osteopenic (23.78
ng/mL) and normal (19.16 ng/mL) subjects (p<0.005). Prevalence of osteopenia and osteoporosis were higher in women than men. The
incidence of osteoporosis was related to the increase of age. Serum osteocalcin level was related to the severity of diagnosis category.

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Submitted

2018-03-13

Accepted

2018-03-13

Published

2018-03-14

How to Cite

[1]
Sennang AN, N., Mutmainnah, M., Pakasi, R. and Hardjoeno, H. 2018. ANALISIS KADAR OSTEOKALSIN SERUM OSTEOPENIA DAN OSTEOPOROSIS. INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 12, 2 (Mar. 2018), 49–52. DOI:https://doi.org/10.24293/ijcpml.v12i2.841.

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