UJI DIAGNOSTIK PLASMODIUM MALARIA MENGGUNAKAN METODE IMUNOKROMATOGRAFI DIPERBANDINGKAN DENGAN PEMERIKSAAN MIKROSKOPIS

Abstract

Microscopic examination is still a gold standard for malaria diagnostic tests. Immunochromatographic (IC) technique can be used
as an alternative examination. The aim is to compare the identification value of immunochromatographic method diagnostic test to
microscopic examination of malaria in laboratory examination. Cross sectional diagnostic study approach was applied to those with
symptoms of: (1) fever (temperature > 38°C) or intermittent fever lasting for two days or more (2) cephalgia/myalgia, 604 samples
were taken consecutively in January to July 2005 from primary health centres of Sukaraja and Keruak, as well as Clinic Nugraha at
Lombok Timur district , province of Nusa Tenggara Barat . From these samples, there were 37 samples with P.vivax, 45 samples with P.
falciparum, 5 samples with mixed infection and 517 samples without Plasmodium sp. From IC examination, results were reserved for 36
samples with P. vivax, 69 samples with P. falciparum, 5 samples with mixed infection and 503 samples without Plasmodium sp. Diagnostic
test data analysis showed that the immunochromatographic test revealed 100% sensitivity, 96.7% specificity, 83.2% positive predictive
value and 100% negative predictive value. It can be concluded that malaria IC test is reliable to be used as a routine malaria test.