KADAR KALIUM DI PACKED RED CELLS SIMPANAN

Abstract

Blood transfusion, is not only transferring the blood cells to the recipient, but also transferring other components such as: glucose,
lactate, and potassium. When the blood is stored, many alterations occur in its cmponents, particularly a decrease of adenosine
5-triphosphate (ATP) and pH, hemolysis, and an increase of potassium levels as well. One of the transfusion complications that should be
avoided is hyperkalemia due to the accumulation of potassium that leaks during the storage. However, hyperkalemia related to transfusion
depends not only on the potassium level in the blood unit, but also on its volume and the rate of its blood administration as well. The
aim of this study was to know the potassium levels in stored Packed Red Cell (PRC). A cohort study was done from May–July 2010. The
researchers used 48 samples from 16 PRCs derived from 16 donors. The samples were drawn from the of PRC hose's plasma that had been
sealed. The potassium levels were measured on the first day, 10th day, and 20th day of the blood collection. The mean potassium level
on the first day was 3.79 mmol/L, 10th day was 12.22 mmol/L and 20th day was 19.77 mmol/L. Comparison of the potassium levels
between the first and 10th day, between first and 20th day, and between 10th and 20th day showed a significant difference (p=0.00). The
increase of potassium levels in the PRC coincide with the storagetime.