D-DIMER PENDERITA SINDROM KORONER AKUT DAN STENOSIS

Abstract

Acute coronary syndrome (ACS) is the multisystem of coronary artery disease. The clinical manifestation of ACS is acute myocardial
infarction (AMI). About 90% coronary attack is caused by thrombus occlusion in coronary artery. The suspect of thrombosis can be
diagnosed definitely by Angiography, but it is invasive. D-dimer used to measure thrombosis abnormality and fibrinolisys. The result of
their correlation between D-dimer with ACS is still controversived. The aim of this research is to analyse, the different between plasma
D-dimer level ACS with stenosis ≥ 50% and stenosis < 50%. This study used a cross sectional design. The study consist of seventeen
specimen ACS with stenosis ≥ 50% and 17 specimen with stenosis < 50%. Plasma D-dimer level was measured with quantitative
agglutination latex method. An independent t-test statistical analysis is used in this study. The average Plasma D-dimer of ACS with
stenosis ≥ 50% is 960.2 ± 404.99 µg/L thus ACS with stenosis < 50% is 300.3 ± 128.75 µg/L (p = 0.00). The plasma D-dimer level
of ACS with stenosis ≥ 50% is more significant than ACS with stenosis < 50%.