Arie Yanti, Uleng Bahrun, Mansyur Arif


Previous studies have shown that neutrophil/lymphocyte ratio in bacteremia is higher than nonbacteremia, therefore it could be
used as a marker to distinguish both conditions in patients with sepsis .Another study on oncology patients in ICU showed a correlation
between the severity of clinical course and the increase of neutrophil/lymphocyte ratio. In physiological condition, neutrophil/lymphocyte
ratio <5, while in pathological conditions (severe infection or systemic inflammation) neutrophil/lymphocyte ratio increases >6.
Neutrophil/lymphocyte ratio is a sensitive, fast, cost effective and applicable laboratory test for routine use, therefore this test result can
be used as the parameter to assess clinical condition of patients. However, a reference value of neutrophil/lymphocyte ratio has never
been defined, especially in Makassar City, South Sulawesi Province. The aim of this study was to know the neutrophil/lymphocyte ratio
in a healthy young adult population. A cross sectional study was conducted from March to April 2014, involving residents (specialistic
candidates in Medical Faculty, Hasanuddin University, who underwwent medical checkup and voluntarily joined this study. Samples
consisted of 198 persons who fulfilled the inclusion criteria with an age range between 24-40 years old, comprising 84 males (42.42%)
and 114 females (57.58%). The neutrophil/lymphocyte ratio for all samples was 1.95 (1.15-4.74). Mann Whitney test showed that
there was no significant difference of neutrophil/lymphocyte ratio between males and females, 1.88 (1.25-4.74) vs 1.95 (1.15-4.12),
p=0.65 and neither between the age group 21-30 years old and 31-40 years old, 1.95 (1.21-4.74) vs 1.94 (1.15-4.09), p=0.82.


Neutrophil, lymphocyte, neutrophil/lymphocyte ratio, young adults

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