KENASABAN FIBRINOGEN PLASMA DENGAN PENEBALAN ARTERI INTIMA-MEDIA KAROTIS KOMUNIS DI DIABETES MELITUS (Correlation Plasma Fibrinogen With Intima-Media Thickness of Carotid Artery in Diabetes Mellitus)

Authors

  • Dwi Aryani
  • Budi Mulyono
  • Osman Sianipar

DOI:

https://doi.org/10.24293/ijcpml.v21i1.1250

Keywords:

Diabetes mellitus, atherosclerosis, carotid IMT, fibrinogen

Abstract

Diabetes mellitus is a global problem due to the increase of its prevalence, morbidity and mortality. Diabetes mellitus has chronic
complications such as : micro vascular and macro vascular. The macro vascular complications reveal as atherosclerosis. The increase of
carotid communist IMT was examined by using USG, which has become the standard for assessing atherosclerosis and recommended by the
American Heart Association. Fibrinogen levels have a role in atherosclerosis. This study was design cross-sectionals to know the association
between plasma fibrinogen with carotid communist IMT in patients with DM by special examination. The subjects were patients with DM
coming to Dr DR. Sardjito Yogyakarta and fulfil the inclusion as well as the exclusion criteria. The examination of fibrinogen was carried out by Claus's method. The result showed positive correlation between plasma fibrinogen with carotid communist IMT in type 2 diabetes mellitus, r = 0.36 and p = 0.021. There is also positive correlation between age and carotid IMT with r = 0.314 and p = 0.048.

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Submitted

2018-04-15

Accepted

2018-04-15

Published

2018-04-15

How to Cite

[1]
Aryani, D., Mulyono, B. and Sianipar, O. 2018. KENASABAN FIBRINOGEN PLASMA DENGAN PENEBALAN ARTERI INTIMA-MEDIA KAROTIS KOMUNIS DI DIABETES MELITUS (Correlation Plasma Fibrinogen With Intima-Media Thickness of Carotid Artery in Diabetes Mellitus). INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 21, 1 (Apr. 2018), 5–10. DOI:https://doi.org/10.24293/ijcpml.v21i1.1250.

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