RERATA VOLUME TROMBOSIT DI DIABETES MELITUS (Mean Platelet Volume in Diabetes Mellitus)

Authors

  • Maria Enrica
  • Nina Tristina
  • Anna Tjandrawati

DOI:

https://doi.org/10.24293/ijcpml.v21i1.1254

Keywords:

Platelet activation, diabetes mellitus, micro and macrovascular complication, mean platelet volume

Abstract

Diabetes Mellitus (DM) is a state of chronically hyperglycemia, which is caused by impaired insulin secretion and function. The
alteration in coagulation system in DM patients served as the basic etiology of macro and micro vascular complication. Platelets are one
of the factors that have a role in the coagulation system and undergo pathological changes in DM patients. Mean Platelet Volume (MPV)
is an indicator of platelet function and activation. Larger platelets have more dense and more reactive pro coagulant granules. The aim
of this study was to know whether there were differences in MPV between DM patients compared to medical check-up participants at
the Dr. Hasan Sadikin Hospital, Bandung.. The research used analytical descriptive, retrospective data. The inclusion criteria of this
research was DM patients and medical check up participants whose serum fasting glucose and two (2) hours post prandial serum glucose
were within the normal range. The data were taken from medical records of DM patients and medical check up participants. The data
were further analyzed with SPSS ver. 15 program using unpaired T-test. In this study, no significant difference between DM patients
and medical check up participants (p>0.05) was found. It can be concluded that Mean Platelet Volume if used as single, can not predict
vascular complication in DM patients.

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Submitted

2018-04-15

Accepted

2018-04-15

Published

2018-04-15

How to Cite

[1]
Enrica, M., Tristina, N. and Tjandrawati, A. 2018. RERATA VOLUME TROMBOSIT DI DIABETES MELITUS (Mean Platelet Volume in Diabetes Mellitus). INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 21, 1 (Apr. 2018), 24–27. DOI:https://doi.org/10.24293/ijcpml.v21i1.1254.

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