Rosita Linda, Devita Ninda


Each year more than 41,000 blood donations are needed every day and 30 million blood components are transfused. Blood products that can be transfused include Packed Red Cells (PRC), Whole Blood (WB), Thrombocyte Concentrate (TC), Fresh Frozen Plasma (FFP). Monitoring Hemoglobin (Hb) after transfusion is essential for assessing the success of a transfusion. The time factor after transfusion for Hemoglobin (Hb) examination needs to be established, analyze to judge the success of a blood transfusion which is performed. The aim of this study was to analyze the differences in changes of hemoglobin between 6-12 hours, and 12-24 hours after-transfusion. This study was retrospective observational using secondary data. The subjects were patients who received PRC, and WBC transfusion. At 6-12, and 12-24 hours after-transfusion, hemoglobin, RBC, and hematocrit were measured. Then the data were analyzed by unpaired t-test. The collected data included the results of the Hb pre-transfusion, 6-12, and 12-24 hours after-transfusion. The subjects of this study were 98 people. The administration of transfusion increased by 10-30% in hemoglobin concentration at 6-12 hours after-transfusion. While at 12-24 hours after-transfusion, hemoglobin after-transfusion increased 15-37% from the baseline. Hemoglobin values were not different at any of the defined after-transfusion times (p = 0.76 (p>0.05)). Hemoglobin values were not different at 6-12 hours, and 12-24 hours after-transfusion.    Keywords: Hemoglobin, measurement, after-transfusion



Hemoglobin, measurement, after-transfusion

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The American National Red Cross, 2013 Annual Report, Accessed at 7th July 2017, www.redcross.org//m39440096_2013AnnualReport.pdf.

US Department of Health & Survey System, National Blood Collection, and Utilization Survey Report. 2012; 2-3, Accessed at 7th July 2017, https://www.aabb.org/bloodsurvey/11-nbcus-report.pdf.

Departemen Kesehatan Republik Indonesia. Modul 2 Pelatihan Crash Program Petugas Teknis Transfusi Darah Bagi Petugas UTDRS, Jakarta, Departemen Kesehatan Republik Indonesia, 2008; 7-10.

Kiswari R. Hematologi & Transfusi, Jakarta, Erlangga Medical Series, 2014; 50-70.

American Society of Hematology. Clinical Practice on Red Blood Cell Transfusion, 2012; 1-4.

Elzik ME, Dirschl RD, Dahners LE. Correlation of Transfusion Volume to Change in Hematocrit, American Journal of Hematology, 2006; 81(2):145-146.

Wakhidah. Evaluasi Waktu Pemeriksaan Kadar Hemoglobin Sesudah Transfusi Darah pada Pasien Anemia di Rumah Sakit Islam Kendal, Skripsi, D4 Analis, Unimus, 2013; 13-15.

Elizalde JI, Clemente J, Marín JL, Panés J, Aragón B, Mas A, Piqué JM, Terés J. Early Changes in Hemoglobin and Hematocrit Levels after Packed Red Cell Transfusion in Patients with Acute Anemia, Transfusion 1997; 37(6): 573–576.

Wiesen AR, Hospenthal DR, Byrd JC, Glass KL, Howard RS, Diehl LF. Equilibration of Hemoglobin Concentration after Transfusion in Medical Inpatients Not Actively Bleeding, Ann Intern Med. 1994; 121(4): 278-280.

Audu LI, Otuneye AT, Mairami AB, Mshelia LJ, Nwatah VE. After Transfusion Hematocrit Equilibration: Timing After Transfusion Hematocrit Check in Neonates at the National Hospital, Abuja, Nigeria, International Journal of Pediatrics, 2015; 2015(2015): 1-5.

Hoque MM, Adnan SD, Karim S, Al Mamun MA, Nandy S, Faruki MA, Mahmud K, Islam K. Equilibration and Increase of Hemoglobin Concentration after One Unit Whole Blood Transfusion Among Patients Not Actively Bleeding, Journal of Dhaka Medical College 2014; 23(2): 161-166.

Naidech AM, Kahn MJ, Soong W, Green D, Batjer H, Bleck TP. Packed Red Blood Cell Transfusion Causes Greater Hemoglobin Rise at a Lower Starting Hemoglobin in Patients with Subarachnoid Hemorrhage, Neurocrit Care 2008; 9(2): 198-203.

Liumbruno G, Bennardello F, Lattanzio A, Piccolo P, Rossetti G. Recommendations for the transfusion of red blood cells, Blood Transfus 2009; 7(1): 49–64.

Zimring JC. Fresh versus old blood: are there differences and do they matter? ASH Education Book, 2013; 2013(1): 651-655.

DOI: http://dx.doi.org/10.24293/ijcpml.v24i2.1306


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