ANALISIS MEAN PLATELET VOLUME (MPV), PLATELET DISTRIBUTION WIDTH (PDW), DAN JUMLAH TROMBOSIT PADA STROKE HEMORAGIK DAN NON HEMORAGIK

Gita Medita Sunusi, Darwati Muhadi, Mansyur Arif

Abstract


Stroke merupakan gangguan fungsional otak fokal maupun global secara mendadak dan akut yang berlangsung lebih dari 24 jam akibat gangguan aliran darah otak (World Health  Organization).  Cedera yang dapat terjadi pada otak dan menyebabkan stroke adalah penyempitan pembuluh darah, sumbatan pembuluh darah, sumbatan atau penyempitan atau pecahnya pembuluh darah sehingga pasokan darah berkurang. Stroke menduduki posisi ke tiga setelah jantung koroner dan kanker di Indonesia.

Stroke diklasifikasi menjadi stroke hemoragik dan stroke non hemoragik. Stroke non hemoragik  merupakan 80% penyebab stroke dan 20% disebabkan stroke hemoragik. Stroke non hemoragik menyebabkan gangguan pasokan oksigen dan nutrisi ke sel-sel otak akibat bentukan trombus atau emboli. Stroke hemoragik intraserebral dan subarachnoid disebabkan pecahnya pembuluh darah kranial.

Keywords


Stroke, MPV, PDW, jumlah trombosit

Full Text:

PDF

References


Setyopranoto I. Stroke : Gejala dan Penatalaksanaan. Available at www.kalbemed.com/portals/6/1_05_185strokegejalapenatalaksanaan. Accesed on Oktober 14th 2016.

Misbach Yusuf, dkk. Guidelines Stroke Tahun 2011. Perhimpunan Dokter Spesialis Saraf Indonesia (PERDOSSI). Jakarta. 2011

Brainin M, Heiss WD. Textbook of Stroke Medicine. Cambrige University Press. 2010

Oz IB, et al. Is Mean Platelet Volume a Reliable Marker to Predict Ischemic Stroke in the Follow-Up of Patients with Carotid Stenosis?. Available at www.ncbi.nlm.nih.gov/pubmed/26576699. Accesed Oktober 8th 2016.

Koklu E, et al. Predictor of Symptom Development in Intermediate Carotid Artery Stenosis: Mean Platelet Volume and Platelet Distribution Width. Available at www. ang.sagepub.com. Accesed September 25th 2016.

Christian, et al. Changes in Haematological Parameters in Stroke Patients in Port Harcort, Nigeria. Available at https://www.ijsr.net/archive/v5i3/NOV161970.pdf. Accesed at June 29th 2016.

Domac FM, et al. Prognostic Role Mean Platelet Volume and Platelet Count in Ischemic and Hemorrhagic Stroke. Available at www.ncbi.nlm.nih.gov/pubmed/20123229. Accesed at June 29th 2016.

Chen Y, et al. The Role of Circulating Platelets Microparticles and Platelet Parameters in Acute Ischemic Stroke Patients. Available at www.ncbi.nlm.nih.gov/pubmed/26169549. Accesed at September 16th 2016.

Du J, et al. Association of mean platelet volume and platelet count with the development and prognosis of ischemic and hemorrhagic stroke. Available at www.ncbi.nlm.nih.gov/pubmed/26992440. Accesed at Oktober 11th 2016.

Sudiono H, Iskandar, Edward H, Halim, SL Santoso R. Penuntun Patologi Klinik Hematologi. Biro Publikasi FK UKRIDA.2009

Tamer D, Fevzi Y, Deniz AE et all. The value of serum mean platelet volume in Ischaemic stroke patient. Available at www.jpma.org.pk/full_article_text.php?article_id=5512. Accesed at at Oktober 11th 2016.

Tohgi H, Hajime S, Tamura K et all. Platelet Volume, Aggregation, and Adenosine Triphosphate Release in Cerebral Thrombosis. Available at http://stroke.ahajournals.org. Accesed at september 31th 2017.

Vagdalti E, Gounari E, Lazaridou E et all. Platelet distribution width : a simple, practical and specific marker of activation of coagulation. Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843567. Accesed at 18th October 2016

Al-Tameemi WF, Ameen AMM. Significance of Platelet Indices in Patients with Acute Ischemic stroke. Available at http://www.colmed-nahrain.edu.iq/. Accesed at August 23th 2017.




DOI: http://dx.doi.org/10.24293/ijcpml.v25i2.1392

Refbacks

  • There are currently no refbacks.