The Compatibility Analysis of Serum Ascites Albumin Gradient and Ascitic Fluid Evaluation to Clinical Diagnosis of the Patient
DOI:
https://doi.org/10.24293/ijcpml.v26i1.1405Keywords:
SAAG, ascitic fluid evaluation, transudate-exudate, clinical diagnosisAbstract
Ascites is a condition of abnormal fluid accumulation in the peritoneal cavity that can be caused by many underlying diseases. Some studies conclude that ascitic fluid evaluation with transudate-exudate concept has been replaced by greater indicator, known as Serum Ascites Albumin Gradient (SAAG). This study aims to analyze the compatibility of SAAG and ascitic fluid evaluation to the clinical diagnosis of patients in Dr. Wahidin Sudirohusodo Hospital Makassar. The retrospective cross-sectional study was conducted by taking data from all patients with ascites condition examining both ascitic fluid and serum albumin simultaneously or within 3 days at the Dr. Wahidin Sudirohusodo Hospital Makassar from January – August 2018. The statistical analysis was performed for frequency distribution and Kappa statistical test to assess the compatibility of SAAG and ascitic fluid evaluation to clinical diagnosis of the patient. The study was conducted on 68 subjects and found that both ascitic fluid examination and SAAG were significantly compatible to the clinical diagnosis, 25.8% (p <0.05), 42.5% (p <0.001), respectively. SAAG and ascitic fluid evaluation were significantly in accordance with the clinical diagnosis of the patient. The compatibility value of SAAG is greater than ascitic fluid evaluation so that SAAG is more recommended for ascites examination.
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References
Fauci AS, et al. Harrison's Manual of Medicine. 19th Ed. New York, The McGraw-Hill Companies, 2014; 271-4.
Appenrodt B. Ascites, Hyponatremia and Hepatorenal Syndrome: Progress in Treatment. Germany, Karger, 2011; 1-10.
Strasinger SK, Lorenzo MS. 6th Ed. Urinalysis and Body Fluids. Philadelphia, F.A. Davis Company, 2014; 237-40.
Sanyal AJ, Bajaj JS, Shaw J. Ascites, Hyponatremia and Hepatorenal Syndrome: Progress in Treatment. Germany, Karger, 2011; 23-31.
Uddin MS, Hogue MI, Islam MB, Mondol G. Serum-ascites albumin gradient in differential diagnosis of ascites. Mymensingh Medical Journal October 2013; https://www.ncbi.nlm.nih.gov/pubmed/24292307 on (accessed July 4, 2018).
Huang LL, Xiang HH, Zhu SL. Ascitic fluid analysis in the differential diagnosis of ascites. Journal of Clinical and Translational Hepatology March 2015; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521252/ on (July 4, 2018).
Younas M, Sattar A, Hashim R, Dilawar M. Role of serum-ascites albumin gradient in differential diagnosis of ascites. Journal of Ayub Medical College December 2012; https://www.ncbi.nlm.nih.gov/pubmed/24669623 on (July 4, 2018).
Brunzel NA. 4th Ed. Fundamentals of Urine and Body Fluid Analysis. Missouri, Elsevier, 2018; 264-5.
Ghany M, Hoofnagle JH. Approach to the Patient with Liver Disease. In: Longo DN, Fauci AS. Second edition of Harrison's Gastroenterology and Hepatology. New York: McGraw Hill; 2013. p. 331-45.
Grace ND, Minor MA. 3rd Ed. Current Diagnosis and Treatment Gastroenterology, Hepatology, and Endoscopy. New York, McGraw Hill, 2016; 562-73.
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