Comparison of Lipid Fractions of Icteric Sample by Using Three Devices

Authors

  • Ummul Khair Hasanuddin University Of Makassar
  • Asvin Nurulita Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar
  • Darwati Muhadi Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

DOI:

https://doi.org/10.24293/ijcpml.v26i1.1412

Keywords:

lipid fraction, icteric sample, pentra, biomajesty, conelab

Abstract

Lipid fraction assessment in laboratory includes cholesterol, HDL, LDL, Triglycerides. The icteric sample is characterized by elevated levels of bilirubin and darkness yellow sample color. This research was to determine the comparison of lipid fraction of icteric sample by using three devices. Cross-sectional study at Clinical Pathology Laboratory of Dr. Wahidin Sudirohusodo of Makassar. Comparison of lipid fraction of icteric samples against 3 (three) devices (Pentra, Biomajesty, Conelab) in period April - June 2018. Statistical analysis using SPSS program. Total sample of 50 indicated that cholesterol level by Biomajesty was lower than Pentra400 (p < 0.001), while the cholesterol level by Conelab was significantly lower than Pentra400 (p > 0.001), but not significantly different with Biomajesty (p < 0.05). HDL level by Biomajesty did not differ significantly with Pentra400 (p > 0.05). HDL level by Conelab were significantly lower than Pentra400 (p < 0.001) and Biomajesty (p < 0.01). HDL level by Biomajesty was smallest than Pentra and Conelab. LDL level by Biomajesty did not differ significantly with Pentra400 (p > 0.05) while LDL level by Conelab was significantly lower than Pentra400 (p < 0.001) and Biomajesty (p < 0.001). It can be seen that the range of TG by Biomajesty is smallest (more accurate) than Pentra400 and Conelab. TG level by Biomajesty was significantly lower than Pentra400 (p < 0.01) while TG level by Conelab was not significantly different than Pentra400 (p > 0.05), but it was significantly higher than Biomajesty (p < 0.001). The research shows that Biomajesty is an accurate device for the measurements of HDL, LDL, and TG of icteric samples, whereas Conelab is an accurate device for cholesterol measurement of icteric samples.

 

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Author Biographies

Asvin Nurulita, Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Darwati Muhadi, Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

References

Stryer, L. Metabolisme Lipid dalam Biokimia Vol 3 Edisi 5. Jakarta. Penerbit Buku Kedokteran. EGC, 2014, hal. 15-25.

Wohlgemuth, R. Lipid Metabolism. In; Biofilesonline Sigma life Science. Vol 7. USA 2013, p.185-189.

Frances K. Tinjauan Klinis atas Hasil Pemeriksaan Laboratorium. Vol 4 Edisi 7. Jakarta. Penerbit Buku Kedokteran. EGC. 2015.hal 57-61.

Bachorik PS, Collection of blood samples for lipoprotein analysis in GR Cooper, Washington, 2014, p.161-176.

NHILB, NIH, National Cholesterol Education Program working group on lipoprotein measurement recommendations, Bettahesda, 2013, p.95-3044.

National Lybrary of Medicine National Institutes of Healt. Icteric human samples. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28397988

Biomajesty ®Jea_BM 6010_CG Diasiys Diagnostic System Gmbh 2013.

Pentra 400 Clinical Chemistry Analyzer, Horiba medical, 2014.

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Submitted

2018-12-11

Accepted

2019-05-13

Published

2019-11-22

How to Cite

[1]
Khair, U., Nurulita, A. and Muhadi, D. 2019. Comparison of Lipid Fractions of Icteric Sample by Using Three Devices. INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 26, 1 (Nov. 2019), 114–117. DOI:https://doi.org/10.24293/ijcpml.v26i1.1412.

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