Antibiotics Susceptibility Pattern of MRSA at Intensive Care Room of Ulin General Hospital Banjarmasin

Shania Indah Chineko, Dewi Indah Noviana Pratiwi, Rahmiati Rahmiati, Noor Muthmainnah, Alfi Yasmina

Abstract


Infection caused by Methicillin-Resistant Staphylococcus aureus (MRSA) is a healthcare-associated infection that
receives the most significant attention worldwide due to its resistance. Administration of precise and rational antibiotics can
prevent high MRSA rates in hospitals. This study aimed to determine the antibiotic susceptibility pattern of MRSA at the
intensive care room of Ulin General Hospital, Banjarmasin, between 2016 and 2018. This study was an observational analytic
study by taking the results of culture and antibiotic susceptibility pattern data of the MRSA isolated from patients treated at
the intensive care room retrospectively. The results showed 37 data of patients suffering from MRSA at the intensive care
room in 2016-2018, with a percentage of 23.81%, 25.81%, and 35.19%, respectively. The most common sources of MRSA
isolate in this study were sputum (32.39%), blood (29.27%), and pus (16.67%). From 2016 to 2017, there was a decreased
susceptibility to macrolide antibiotics, aminoglycosides such as Gentamicin, and quinolones such as Moxifloxacin. In 2018,
there was an increased susceptibility pattern of some antibiotics compared to the previous period. Antibiotics with the
highest susceptibility in period of 2016-2018 were Linezolid, Quinupristin/Dalfopristin, Tigecycline, Nitrofurantoin, and
Trimethoprim/Sulfamethoxazole. Also, the antibiotic with the lowest susceptibility was Tetracycline. It was concluded that
there had been changes in some antibiotics' susceptibility pattern to MRSA within 2016-2018.


Keywords


Methicillin-resistant Staphylococcus aureus, susceptibility, antibiotics, intensive care room

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DOI: http://dx.doi.org/10.24293/ijcpml.v27i2.1649

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