The Relationship of Neutrophil-Lymphocyte Ratio and Glycemic Control in Type 2 Diabetes Mellitus Patients

Authors

  • Nurahmi Nurahmi Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Wahidin Sudirohusodo Hospital, Makassar
  • Budi Mulyono Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta
  • Windarwati Windarwati Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta

DOI:

https://doi.org/10.24293/ijcpml.v28i1.1739

Keywords:

Diabetes mellitus, NLR, glycemic control

Abstract

Progressivity of type 2 Diabetes Mellitus (DM) is associated with a condition of chronic inflammation. The Neutrophil-Lymphocyte Ratio (NLR) has become a potential new marker of inflammation to detect chronic inflammation. This research aimed to determine NLR differences between controlled type 2 DM and uncontrolled type 2 DM groups. This research conducted an observational with a cross-sectional approach to 56 patients with type 2 diabetes. The identity, anthropometric measurements, and laboratory data of routine blood exam and HbA1c were carried out on each research subject, and then the NLR calculations were performed. The subjects were 20 (35.70%) controlled type 2 DM patients, 36 (64.30%) uncontrolled type 2 DM patients, consisting of 36 (64.30%) male and 20 (35.70%) females. The NLR value was statistically significantly higher in uncontrolled type 2 DM patients than controlled type 2 DM patients, which was 1.90±0.84 compared to 1.52±0.50 (p=0.035). There was a significant difference in the NLR value between the uncontrolled type 2 DM group and the controlled type 2 DM group.

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Author Biographies

Nurahmi Nurahmi, Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Wahidin Sudirohusodo Hospital, Makassar

Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Wahidin Sudirohusodo Hospital, Makassar

Budi Mulyono, Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta

Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta

Windarwati Windarwati, Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta

Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta

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Submitted

2020-11-23

Accepted

2021-08-03

Published

2021-12-15

How to Cite

[1]
Nurahmi, N., Mulyono, B. and Windarwati, W. 2021. The Relationship of Neutrophil-Lymphocyte Ratio and Glycemic Control in Type 2 Diabetes Mellitus Patients. INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 28, 1 (Dec. 2021), 14–16. DOI:https://doi.org/10.24293/ijcpml.v28i1.1739.

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