The Relationship between Blood Gas Analysis Profile and the Outcome of Severe COVID-19 Patients

Authors

  • Helena Sembai Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar
  • Sulina Yanti Wibawa Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Stella Maris General Hospital, Makassar
  • Irda Handayani Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar
  • Darmawaty ER. Rauf Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Faisal Islamic Hospital, Makassar

DOI:

https://doi.org/10.24293/ijcpml.v29i3.2017

Keywords:

COVID-19, SARS-Cov-2, rt-PCR, intensive care unit, blood gas analysis

Abstract

Coronaviruses commonly infect the respiratory tract, leading to severe pneumonia. Respiratory problems cause numerous acid-base disorders in 2019 Coronavirus Disease (COVID-19) patients. Several studies have explored laboratory biomarkers used in the management and prognosis of COVID-19 patients during this pandemic; however, only a few focused on blood gas analysis. Determine the blood gas analysis pattern and its association with the outcome of severe COVID-19 patients treated in the Intensive Care Unit (ICU). This retrospective cohort study used secondary data from patients with severe COVID-19 treated in the ICU of Hasanuddin University Hospital between January and December 2021. There was a higher number of male (58.8%) compared to female patients (41.5%), with a mean age of 62 years. Respiratory alkalosis was the most prevalent blood gas disorder (24.4%). Metabolic alkalosis was a blood gas disorder with the highest number of recovery/improvement outcomes (8 patients). There was no significant relationship between blood gas analysis results and the outcome of severe COVID-19. In addition, no specific pattern was found in the results of blood gas analysis. Respiratory alkalosis was the most frequent blood gas disorder detected in these patients.

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Author Biographies

Helena Sembai, Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Sulina Yanti Wibawa, Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Stella Maris General Hospital, Makassar

Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Stella Maris General Hospital, Makassar

Irda Handayani, Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar

Darmawaty ER. Rauf, Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Faisal Islamic Hospital, Makassar

Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo Hospital, Makassar; Faisal Islamic Hospital, Makassar

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Submitted

2022-07-25

Accepted

2023-03-08

Published

2023-07-27

How to Cite

[1]
Sembai, H., Wibawa, S.Y., Handayani, I. and Rauf, D.E. 2023. The Relationship between Blood Gas Analysis Profile and the Outcome of Severe COVID-19 Patients . INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 29, 3 (Jul. 2023), 296–299. DOI:https://doi.org/10.24293/ijcpml.v29i3.2017.

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