POLA KUMAN BERDASARKAN SPESIMEN DAN SENSITIVITAS TERHADAP ANTIMIKROBA

Abstract

High prevalence of infectious diseases in Indonesia lead to the use of uncontrollable anti microbial treatment with less concern to
drug resistance, marked with fewer requests for sensitivity testing. This leads to irrational anti microbial treatment and increasing drug
resistance. With unsupported condition for using a sensitivity test prior to anti microbial treatment, a common guide for choosing an
anti microbial agent for infection of specific organ system is needed. A descriptive study of retrospectively collected data of sensitivity test
results was done on 841 spesimens from sources of infected organs in Wahidin Sudirohusodo Hospital of Makassar during 2005–2006
periods. Objectives of this study are to know the microbial pattern of specific organ infection (represented by microbes of the specimens),
antimicrobial sensitivity pattern of the microorganisms, and whether there is shifting of the pattern within a 1 year period. Shifting
of microbial patterns during 2005–2006 period was found. Klebsiella aeroginosa, Enterobacter agglomerans, Alkaligenes faecalis and
Escherichia coli were the most frequent micro organisms found from spesimens examined. Most of antimicrobial drugs commonly
used were found effective to most of micro organisms, while amikacin, cefepime, gentamycin, sulbactam, tobramycin, vancomycin and
meropene were still sensitive enough to the majority of the infectious agents.